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Mat. Biolog. Bioinform., 2012, Volume 7, Issue 2, Pages 372–397 (Mi mbb111)  

Mathematical Modeling

A review of computational models of neuronal cultures in vitro

Konstantin V. Anokhin, Mikhail S. Burtsev, Viachesav A. Ilyin, Ilya I. Kiselev, Konstantin A. Kukin, Konstantin V. Lakhman, Alexander V. Paraskevov, Roman B. Rybka, Alexander G. Sboev, Nikolay V. Tverdokhlebov

National Research Center "Kurchatov Institute", Moscow, 123182, Russia

Abstract: One of the widely used experimental models in modern neuroscience is neuronal cultures in vitro. Neural networks cultured on multielectrode arrays allow to record large amount of information about the dynamics of neuronal activity, as well as to activate the cells by electrical stimulation. It makes the neuronal cultures a convenient tool for verification of theoretical models of neural networks. The main approaches to computer modeling of the dynamics of activity in the neuron cultures are considered in this review.

Key words: neuron, neuronal culture, synaptic plasticity, multielectrode array, spiking dynamics of neural networks.

Full text: PDF file (3362 kB)
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UDC: 51-76
Received 28.06.2012, Published 16.07.2012

Citation: Konstantin V. Anokhin, Mikhail S. Burtsev, Viachesav A. Ilyin, Ilya I. Kiselev, Konstantin A. Kukin, Konstantin V. Lakhman, Alexander V. Paraskevov, Roman B. Rybka, Alexander G. Sboev, Nikolay V. Tverdokhlebov, “A review of computational models of neuronal cultures in vitro”, Mat. Biolog. Bioinform., 7:2 (2012), 372–397

Citation in format AMSBIB
\Bibitem{AnoBurIly12}
\by Konstantin~V.~Anokhin, Mikhail~S.~Burtsev, Viachesav~A.~Ilyin, Ilya~I.~Kiselev, Konstantin~A.~Kukin, Konstantin~V.~Lakhman, Alexander~V.~Paraskevov, Roman~B.~Rybka, Alexander~G.~Sboev, Nikolay~V.~Tverdokhlebov
\paper A review of computational models of neuronal cultures \emph{in vitro}
\jour Mat. Biolog. Bioinform.
\yr 2012
\vol 7
\issue 2
\pages 372--397
\mathnet{http://mi.mathnet.ru/mbb111}


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