RUS  ENG JOURNALS   PEOPLE   ORGANISATIONS   CONFERENCES   SEMINARS   VIDEO LIBRARY   PACKAGE AMSBIB
General information
Latest issue
Archive
Impact factor

Search papers
Search references

RSS
Latest issue
Current issues
Archive issues
What is RSS



Mat. Biolog. Bioinform.:
Year:
Volume:
Issue:
Page:
Find






Personal entry:
Login:
Password:
Save password
Enter
Forgotten password?
Register


Mat. Biolog. Bioinform., 2012, Volume 7, Issue 2, Pages 611–631 (Mi mbb126)  

Bioinformatics

Comparative Analysis of Individual Domains of Hoc Proteins in Subfamily Teequatrovirinae Bacteriophages

Andrey A. Zimina, Galina V. Mikoulinskaiab, Lira F. Nigmatullinaa, Nafisa N. Nazipovac

a G. K. Skryabin Institute of biochemistry and physiology of microorganisms of the RAS
b The Branch of the M. M. Shemyakin--Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of the RAS
c Institute of Mathematical Problems of Biology of the RAS

Abstract: This paper presents the results of a comparative study of the immunoglobulin-like domains in the genomes of phages related to bacteriophage T4. It is proposed to use Hoc proteins for the classification of subfamily Teequatrovirinae phages. A phylogenetic analysis was conducted for Hoc protein domains from 31 bacteriophages of the subfamily . It is shown that the number of domains in proteins of various bacteriophages of the subfamily varies from one to five. According to these findings the bacteriophages can be divided into six sub-groups. The phylogenetic tree of the protein domains of T4-related bacteriophages forms three main branches. Obligatory presence of the C-terminal domain in all proteins points to its functional and structural importance for the formation of the protein and its ability to attach to the phage capsid. A hypothetical scheme is formulated of the evolutionary origin of repeated amino acid sequences in Hoc proteins.

Key words: bacteriophage T4, Hoc protein, immunoglobulin-like proteins, domains, phylogenetic tree, protein evolution.

Full text: PDF file (607 kB)
References: PDF file   HTML file
UDC: 578.81, 51-76
Received 11.10.2012, Published 26.11.2012

Citation: Andrey A. Zimin, Galina V. Mikoulinskaia, Lira F. Nigmatullina, Nafisa N. Nazipova, “Comparative Analysis of Individual Domains of Hoc Proteins in Subfamily Teequatrovirinae Bacteriophages”, Mat. Biolog. Bioinform., 7:2 (2012), 611–631

Citation in format AMSBIB
\Bibitem{ZimMikNig12}
\by Andrey~A.~Zimin, Galina~V.~Mikoulinskaia, Lira~F.~Nigmatullina, Nafisa~N.~Nazipova
\paper Comparative Analysis of Individual Domains of Hoc Proteins in Subfamily \emph{Teequatrovirinae} Bacteriophages
\jour Mat. Biolog. Bioinform.
\yr 2012
\vol 7
\issue 2
\pages 611--631
\mathnet{http://mi.mathnet.ru/mbb126}


Linking options:
  • http://mi.mathnet.ru/eng/mbb126
  • http://mi.mathnet.ru/eng/mbb/v7/i2/p611

    SHARE: VKontakte.ru FaceBook Twitter Mail.ru Livejournal Memori.ru


    Citing articles on Google Scholar: Russian citations, English citations
    Related articles on Google Scholar: Russian articles, English articles
    Translation
  • Number of views:
    This page:267
    Full text:50
    References:26
    First page:1

     
    Contact us:
     Terms of Use  Registration  Logotypes © Steklov Mathematical Institute RAS, 2020