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Mat. Biolog. Bioinform., 2008, Volume 3, Issue 1, Pages 1–15 (Mi mbb33)  

Bioinformatics

Search of regular sequences in promoters from various genomes using runs test

A. A. Shelenkov, E. V. Korotkov

Centre "Bioengineering", Russian Academy of Sciences, Moscow, Russia

Abstract: In this paper, a notion of “regularity” is introduced to describe the structural features of DNA sequences. This notion expands the “latent periodicity” term. A novel method for revealing regularity based on the runs test is given. The search of regular sequences in eukaryotic promoters has shown that more than 60% of them possess the regularity property on statistically significant level. Possible biological functions of regularity are discussed together with possibility of using this characteristic for making promoter annotation.

Key words: regularity, promoters, DNA sequences.

Full text: PDF file (433 kB)
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UDC: 577.212.2
Received 17.03.2008, Published 17.04.2008

Citation: A. A. Shelenkov, E. V. Korotkov, “Search of regular sequences in promoters from various genomes using runs test”, Mat. Biolog. Bioinform., 3:1 (2008), 1–15

Citation in format AMSBIB
\Bibitem{SheKor08}
\by A.~A.~Shelenkov, E.~V.~Korotkov
\paper Search of regular sequences in promoters from various genomes using runs test
\jour Mat. Biolog. Bioinform.
\yr 2008
\vol 3
\issue 1
\pages 1--15
\mathnet{http://mi.mathnet.ru/mbb33}


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