RUS  ENG JOURNALS   PEOPLE   ORGANISATIONS   CONFERENCES   SEMINARS   VIDEO LIBRARY   PACKAGE AMSBIB
General information
Latest issue
Archive
Impact factor

Search papers
Search references

RSS
Latest issue
Current issues
Archive issues
What is RSS



Mat. Biolog. Bioinform.:
Year:
Volume:
Issue:
Page:
Find






Personal entry:
Login:
Password:
Save password
Enter
Forgotten password?
Register


Mat. Biolog. Bioinform., 2009, Volume 4, Issue 2, Pages 46–51 (Mi mbb44)  

This article is cited in 2 scientific papers (total in 2 papers)

Mathematical Modeling

On the possibility of superfast charge transfer in DNA

V. D. Lakhno, V. B. Sultanov

Institute of Mathematical Problems of Biology, Russian Academy of Sciences

Abstract: Numerous experiments on charge transfer in DNA yield a contradictory picture of the transfer: on the one hand they suggest that it is a very slow process and the charge is almost completely localized on one Watson–Crick pair, but on the other hand they demonstrate that the charge can travel a very large distance. To explain this contradiction we propose that superfast charge transitions are possible between base pairs on individual DNA fragments resulting in the establishment of a quasi-equilibrium charge distribution during the time less than that of charge solvation. In other words, we hypothesize these states irrespective of the nature of a mechanism responsible for their establishment, whether it be a hopping mechanism, or a band mechanism, or superexchange, or polaron transport, etc., leaving aside the debates of which one is more advantageous. We discuss qualitative differences between the charge transfer in a dry DNA and that in a solution. In a solution, of great importance is the charge solvation which decreases the transfer rate $10^7\div10^8$ times as compared with a dry DNA. We consider the conditions under which the superfast charge transfer in a DNA leading to quasiequilibrium distributions of polarons in a duplex is possible. Comparison of calculated quasi-equilibrium distributions with the experiment testifies to the possibility of superfast tunnel transitions of a hole in a DNA duplex in a solution.

Key words: Holstein Hamiltonian, hole, solvation.

Full text: PDF file (270 kB)
References: PDF file   HTML file

English version:
Mathematical Biology and Bioinformatics, 2009, 4:2, 1–6
UDC: 577, 51-7
Received 16.06.2009, Published 06.07.2009

Citation: V. D. Lakhno, V. B. Sultanov, “On the possibility of superfast charge transfer in DNA”, Mat. Biolog. Bioinform., 4:2 (2009), 46–51; Mat. Biolog. Bioinform., 4:2 (2009), 1–6

Citation in format AMSBIB
\Bibitem{LakSul09}
\by V.~D.~Lakhno, V.~B.~Sultanov
\paper On the possibility of superfast charge transfer in DNA
\jour Mat. Biolog. Bioinform.
\yr 2009
\vol 4
\issue 2
\pages 46--51
\mathnet{http://mi.mathnet.ru/mbb44}
\transl
\jour Mat. Biolog. Bioinform.
\yr 2009
\vol 4
\issue 2
\pages 1--6


Linking options:
  • http://mi.mathnet.ru/eng/mbb44
  • http://mi.mathnet.ru/eng/mbb/v4/i2/p46

    SHARE: VKontakte.ru FaceBook Twitter Mail.ru Livejournal Memori.ru


    Citing articles on Google Scholar: Russian citations, English citations
    Related articles on Google Scholar: Russian articles, English articles

    This publication is cited in the following articles:
    1. D. A. Tikhonov, E. V. Sobolev, V. D. Lakhno, N. S. Fialko, “Adiabaticheskoe priblizhenie pri raschetakh podvizhnosti zaryada v kholsteinovskoi modeli DNK”, Matem. biologiya i bioinform., 6:2 (2011), 264–272  mathnet
    2. Lakhno V.D., Fialko N.S., “Solvation Effects on Hole Mobility in the Poly G/Poly C Duplex”, Russ. J. Phys. Chem. A, 86:5 (2012), 832–836  crossref  isi  elib  elib  scopus
  • Number of views:
    This page:212
    Full text:72
    References:18
    First page:1

     
    Contact us:
     Terms of Use  Registration  Logotypes © Steklov Mathematical Institute RAS, 2019