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Kvantovaya Elektronika, 2006, Volume 36, Number 12, Pages 1125–1130 (Mi qe13457)  

This article is cited in 6 scientific papers (total in 6 papers)

Special issue devoted to multiple radiation scattering in random media

Simulations of a spatially resolved reflectometry signal from a highly scattering three-layer medium applied to the problem of glucose sensing in human skin

A. V. Bykovabc, M. Yu. Kirillinac, A. V. Priezzhevab, R. A. Myllyläc

a Faculty of Physics, Lomonosov Moscow State University
b International Laser Center of Moscow State University
c Department of Electrical and Information Engineering, Optoelectronics and Measurement Techniques Laboratory, University of Oulu, Finland

Abstract: The possibility of using spatially resolved reflectometry (SRR) at a wavelength of 820 nm to detect changes in the optical properties of a highly scattering layered random medium simulating a biological tissue caused by changes in the glucose level is analysed. Model signals from a three-layer biological tissue phantom consisting of two skin layers and a blood layer located between them are obtained by the Monte-Carlo method. It was assumed that variations in the glucose level induce variations in the optical parameters of the blood layer and the bottom skin layer. To analyse the trajectories of photons forming the SRR signal, their scattering maps are obtained. The ratio of the photon path in layers sensitive to the glucose level to the total path in the medium was used as a parameter characterising these trajectories. The relative change in the reflected signal caused by a change in the glucose concentration is analysed depending on the distance between a probe radiation source and a detector. It is shown that the maximum relative change in the signal (about 7%) takes place for the source – detector separation in the range from 0.3 to 0.5 mm depending on the model parameters.

Full text: PDF file (194 kB)

English version:
Quantum Electronics, 2006, 36:12, 1125–1130

Bibliographic databases:

PACS: 42.30.Wb, 87.64.Cc, 05.10.Ln
Received: 10.08.2006

Citation: A. V. Bykov, M. Yu. Kirillin, A. V. Priezzhev, R. A. Myllylä, “Simulations of a spatially resolved reflectometry signal from a highly scattering three-layer medium applied to the problem of glucose sensing in human skin”, Kvantovaya Elektronika, 36:12 (2006), 1125–1130 [Quantum Electron., 36:12 (2006), 1125–1130]

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    Citing articles on Google Scholar: Russian citations, English citations
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    This publication is cited in the following articles:
    1. V. S. Kuznetsov, O. V. Nikolaeva, L. P. Bass, A. V. Bykov, A. V. Priezzhev, Math. Models Comput. Simul., 2:1 (2010), 22–32  mathnet  crossref
    2. Haiyan Cen, Renfu Lu, Opt Express, 18:16 (2010), 17412  crossref  isi  scopus
    3. Quantum Electron., 40:12 (2010), 1067–1073  mathnet  crossref  isi  elib
    4. Zhenzhi Shi, Ying Fan, Huijuan Zhao, Kexin Xu, J. Biomed. Opt, 17:6 (2012), 067004  crossref  isi  scopus
    5. Lu R., Cen H., Hyperspectral Imaging Technology in Food and Agriculture, Food Engineering Series, eds. Park B., Lu R., Springer, 2015, 203–226  crossref  isi  scopus
    6. Myllyla T., Harju M., Korhonen V., Bykov A., Kiviniemi V., Meglinski I., J. Biophotonics, 11:8, SI (2018), UNSP e201700123  crossref  isi  scopus
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