This article is cited in 1 scientific paper (total in 1 paper)
Laser applications in biology and medicine
Online determination of biophysical parameters of mucous membranes of a human body
S. A. Lisenko, M. M. Kugeiko
Belarusian State University, Minsk
We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measurements of spectral and spatial characteristics of diffuse reflection. The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method.
endoscopy, mucous membrane, optical parameters, biophysical parameters, diffuse reflectance, optical measurements, inverse problem, multiple regressions.
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Quantum Electronics, 2013, 43:7, 683–689
42.62.Be, 87.64.Cc, 07.60.Vg
S. A. Lisenko, M. M. Kugeiko, “Online determination of biophysical parameters of mucous membranes of a human body”, Kvantovaya Elektronika, 43:7 (2013), 683–689 [Quantum Electron., 43:7 (2013), 683–689]
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