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Kvantovaya Elektronika, 2014, Volume 44, Number 8, Pages 726–731 (Mi qe16022)  

This article is cited in 1 scientific paper (total in 1 paper)

Laser biophotonics

Multimodal diagnosis and visualisation of oncologic pathologies

V. P. Zakharova, I. A. Bratchenkoa, O. O. Myakinina, D. N. Artemyeva, D. V. Kornilina, S. V. Kozlovb, A. A. Moryatovb

a S. P. Korolyov Samara State Aerospace University
b Samara State Medical University

Abstract: The combined application of optical coherence tomography, Raman and autofluorescence spectroscopy of biotissues for the analysis of human malignant neoplasms is demonstrated. Rapid investigation of vast biotissue regions (at the scale of entire organs) is possible using the autofluorescence response. After selection of possible zones of pathologies one can visualise the neoplasm topology in the zone of interest with micron precision by using optical coherence tomography. In the case of suspecting the malignancy the analysis of the biotissue Raman spectrum is carried out that allows identification of the neoplasm type with the sensitivity and specificity ~85%. An experimental scheme is proposed with the combined use of the abovementioned methods, which is a prototype of the medical system for complex analysis of neoplasms.

Keywords: multimodal diagnosis, noninvasive diagnosis, optical coherence tomography, Raman scattering, autofluorescence analysis.

Full text: PDF file (1323 kB)
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English version:
Quantum Electronics, 2014, 44:8, 726–731

Bibliographic databases:

PACS: 87.19.xj, 87.57.Q-, 87.64.kp, 87.64.kv
Received: 16.04.2014
Revised: 15.06.2014

Citation: V. P. Zakharov, I. A. Bratchenko, O. O. Myakinin, D. N. Artemyev, D. V. Kornilin, S. V. Kozlov, A. A. Moryatov, “Multimodal diagnosis and visualisation of oncologic pathologies”, Kvantovaya Elektronika, 44:8 (2014), 726–731 [Quantum Electron., 44:8 (2014), 726–731]

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  • http://mi.mathnet.ru/eng/qe/v44/i8/p726

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    Citing articles on Google Scholar: Russian citations, English citations
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    This publication is cited in the following articles:
    1. Artemyev D.N., Zakharov V.P., Davydkin I.L., Khristoforova J.A., Lykina A.A., Konyukhov V.N., Kuzmina T.P., Opt. Quantum Electron., 48:6 (2016), 337  crossref  isi  scopus
  • Квантовая электроника Quantum Electronics
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