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Kvantovaya Elektronika, 2020, Volume 50, Number 1, Pages 69–75 (Mi qe17176)  

This article is cited in 2 scientific papers (total in 2 papers)

Topical issues of biophotonics

Structural and optical properties of nanoparticles formed by laser ablation of porous silicon in liquids: Perspectives in biophotonics

S. V. Zabotnova, D. A. Kurakinab, F. V. Kashaeva, A. V. Skobelkinaa, A. V. Kolchina, T. P. Kaminskayaa, A. V. Khilovb, P. D. Agrbaca, E. A. Sergeevaba, P. K. Kashkarova, M. Yu. Kirillinb, L. A. Golovana*

a Faculty of Physics, Lomonosov Moscow State University
b Federal Research Center The Institute of Applied Physics of the Russian Academy of Sciences, Nizhny Novgorod
c National Research Lobachevsky State University of Nizhny Novgorod

Abstract: The paper discusses the possibility of manufacturing silicon nanoparticles, which are suitable for contrasting biological tissues imaged by optical coherence tomography, by femtosecond laser ablation of porous silicon in various liquids. The manufactured nanoparticles are characterised by average sizes of 87, 112, and 102 nm for cases of ablation in water, ethanol, and liquid nitrogen, respectively, as well as a relatively narrow size distribution, which provides additional advantages for subsequent delivery into biological tissues. Electrochemical etching, which results in the formation of layers of porous silicon, allows the yield of ablation products to be increased severalfold by lowering the ablation threshold, thereby increasing the light scattering efficiency of the prepared suspensions compared with the case of using crystalline silicon as targets. The possibility of obtaining high-contrast images of a biotissue phantom based on an agar gel with embedded nanoparticles is shown. The magnitude of the contrast depends on the liquid used for ablation and correlates with the values of the reduced scattering coefficient of the studied suspensions.

Keywords: silicon nanoparticles, laser ablation in liquids, atomic force microscopy, light scattering, spectrophotometry, optical coherence tomography.

Funding Agency Grant Number
Russian Science Foundation 19-12-00192

* Author to whom correspondence should be addressed

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English version:
Quantum Electronics, 2020, 50:1, 69–75

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Received: 27.11.2019

Citation: S. V. Zabotnov, D. A. Kurakina, F. V. Kashaev, A. V. Skobelkina, A. V. Kolchin, T. P. Kaminskaya, A. V. Khilov, P. D. Agrba, E. A. Sergeeva, P. K. Kashkarov, M. Yu. Kirillin, L. A. Golovan, “Structural and optical properties of nanoparticles formed by laser ablation of porous silicon in liquids: Perspectives in biophotonics”, Kvantovaya Elektronika, 50:1 (2020), 69–75 [Quantum Electron., 50:1 (2020), 69–75]

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  • http://mi.mathnet.ru/eng/qe/v50/i1/p69

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    Citing articles on Google Scholar: Russian citations, English citations
    Related articles on Google Scholar: Russian articles, English articles

    This publication is cited in the following articles:
    1. Zabotnov V S., Skobelkina V A., Sergeeva E.A., Kurakina D.A., Khilov V A., Kashaev V F., Kaminskaya T.P., Presnov D.E., Agrba P.D., Shuleiko V D., Kashkarov P.K., Golovan L.A., Kirillin M.Yu., Sensors, 20:17 (2020), 4874  crossref  isi
    2. Quantum Electron., 51:1 (2021), 64–72  mathnet  crossref  isi  elib
  • Квантовая электроника Quantum Electronics
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