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Usp. Khim., 2018, Volume 87, Issue 6, Pages 509–552 (Mi rcr4211)  

Arbidol: a quarter-century later. Past, present and future of the original Russian antiviral

Konstantin V. Balakinab, Rosanna Filosacde, Sergey N. Lavrenovf, Arthur S. Mkrtchyang, Maxim B. Nawrozkijg, Ivan A. Novakovg

a Kazan (Volga Region) Federal University
b I. M. Sechenov First Moscow State Medical University
c Department of Experimental Medicine, Section of Biotechnology, University of Campania "Luigi Vanvitelli", Italy
d Consorzio Sannio Tech, Italy
e Institute of Food Sciences, National Research Council, Italy
f Gause Institute of New Antibiotics, Moscow
g Volgograd State Technical University

Abstract: The present review relates to the synthesis and structure-activity relationship studies of Arbidol and its structural analogues. The latter are roughly divided into several unequal parts: indole- and benzofuran-based compounds, benzimidazole and imidazopyridine bioisosteres, and ring-expanded quinoline derivatives. Much attention is focused on various types of antiviral activity of the above-mentioned Arbidol congeners, as well as of the parent compound itself. Features of Arbidol synthesis and metabolic changes are also discussed.
Bibliography — 166 references.

Funding Agency Grant Number
Russian Foundation for Basic Research 16-33-6003 mol_a_dk
Ministry of Education and Science of the Russian Federation


Full text: http://www.uspkhim.ru/.../paper_rus.phtml?journal_id=rc&paper_id=4791

English version:
Russian Chemical Reviews, 2018, 87:6, 509–552

Document Type: Article
Received: 18.10.2017
Language: English

Citation: Konstantin V. Balakin, Rosanna Filosa, Sergey N. Lavrenov, Arthur S. Mkrtchyan, Maxim B. Nawrozkij, Ivan A. Novakov, “Arbidol: a quarter-century later. Past, present and future of the original Russian antiviral”, Usp. Khim., 87:6 (2018), 509–552; Russian Chem. Reviews, 87:6 (2018), 509–552

Citation in format AMSBIB
\Bibitem{BalFilLav18}
\by Konstantin~V.~Balakin, Rosanna~Filosa, Sergey~N.~Lavrenov, Arthur~S.~Mkrtchyan, Maxim~B.~Nawrozkij, Ivan~A.~Novakov
\paper Arbidol: a quarter-century later. Past, present and future of the original Russian antiviral
\jour Usp. Khim.
\yr 2018
\vol 87
\issue 6
\pages 509--552
\mathnet{http://mi.mathnet.ru/rcr4211}
\transl
\jour Russian Chem. Reviews
\yr 2018
\vol 87
\issue 6
\pages 509--552
\crossref{https://doi.org/10.1070/RCR4791}
\scopus{http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85048057986}


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