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Usp. Khim., 2018, Volume 87, Issue 6, Pages 604–618 (Mi rcr4214)  

Purine derivatives with antituberculosis activity

D. A. Gruzdev, V. V. Musiyak, G. L. Levit, V. P. Krasnov, V. N. Charushin

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg

Abstract: The review summarizes the data published over the last 10–15 years concerning the key groups of purine derivatives with antituberculosis activity. The structures of purines containing heteroatoms (S, O, N), fragments of heterocycles, amino acids and peptides, in the 6-position, as well as of purine nucleosides are presented. The possible targets for the action of such compounds and structure–activity relationship are discussed. Particular attention is paid to the most active compounds, which are of considerable interest as a basis for the development of efficient antituberculosis drugs.
The bibliography includes 99 references.

Funding Agency Grant Number
Russian Science Foundation 14-13-01077


Full text: http://www.uspkhim.ru/.../paper_rus.phtml?journal_id=rc&paper_id=4772

English version:
Russian Chemical Reviews, 2018, 87:6, 604–618

Bibliographic databases:

Document Type: Article
Received: 03.08.2017

Citation: D. A. Gruzdev, V. V. Musiyak, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Purine derivatives with antituberculosis activity”, Usp. Khim., 87:6 (2018), 604–618; Russian Chem. Reviews, 87:6 (2018), 604–618

Citation in format AMSBIB
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\by D.~A.~Gruzdev, V.~V.~Musiyak, G.~L.~Levit, V.~P.~Krasnov, V.~N.~Charushin
\paper Purine derivatives with antituberculosis activity
\jour Usp. Khim.
\yr 2018
\vol 87
\issue 6
\pages 604--618
\mathnet{http://mi.mathnet.ru/rcr4214}
\transl
\jour Russian Chem. Reviews
\yr 2018
\vol 87
\issue 6
\pages 604--618
\crossref{https://doi.org/10.1070/RCR4772}
\isi{http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&DestLinkType=FullRecord&DestApp=ALL_WOS&KeyUT=000437806900004}
\scopus{http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85048052919}


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