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UFN, 2010, Volume 180, Number 9, Pages 931–956 (Mi ufn2269)  

This article is cited in 29 scientific papers (total in 29 papers)


Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor

Yu. M. Romanovsky, A. N. Tikhonov

M. V. Lomonosov Moscow State University, Faculty of Physics, Moscow, Russian Federation

Abstract: The free energy released upon the fermentative hydrolysis of adenosine triphosphate (ATP) is the main source of energy for functioning of the living cell and all multicellular organisms. The overwhelming majority of ATP molecules are formed by proton ATP syntheses, which are the smallest macromolecular electric motors in nature. This paper reviews the modern concepts of the molecular structure and functioning of the proton ATP synthase, and real-time biophysical experiments on the rotation of the ‘rotor’ of this macromolecular motor. Some mathematical models describing the operation of this nanosized macromolecular machine are described.


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English version:
Physics–Uspekhi, 2010, 53:9, 893–914

Bibliographic databases:

PACS: 87.10.-e, 87.15.-v, 87.16.-b
Received: March 26, 2010
Revised: April 23, 2010

Citation: Yu. M. Romanovsky, A. N. Tikhonov, “Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor”, UFN, 180:9 (2010), 931–956; Phys. Usp., 53:9 (2010), 893–914

Citation in format AMSBIB
\by Yu.~M.~Romanovsky, A.~N.~Tikhonov
\paper Molecular energy transducers of the living cell. Proton ATP synthase: a rotating molecular motor
\jour UFN
\yr 2010
\vol 180
\issue 9
\pages 931--956
\jour Phys. Usp.
\yr 2010
\vol 53
\issue 9
\pages 893--914

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    This publication is cited in the following articles:
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    18. Ikryannikova L.N., Ischenko D.S., Lominadze G.G., Kanygina A.V., Karpova I.Y., Kostryukova E.S., Mayansky N.A., Skvortsov V.S., Ilina E.N., Govorun V.M., “the Mystery of the Fourth Clone: Comparative Genomic Analysis of Four Non-Typeable Streptococcus Pneumoniae Strains With Different Susceptibilities To Optochin”, Eur. J. Clin. Microbiol. Infect. Dis., 35:1 (2016), 119–130  crossref  isi  scopus
    19. Nath S., “The thermodynamic efficiency of ATP synthesis in oxidative phosphorylation”, Biophys. Chem., 219 (2016), 69–74  crossref  isi  elib  scopus
    20. Ivontsin L.A., Mashkovtseva E.V., Nartsissov Ya.R., “Simulation of Proton Movement in F0F1-Atp Synthase By Quantum-Mechanical Approach”, 1st International Symposium Physics, Engineering and Technologies For Bio-Medicine, Journal of Physics Conference Series, 784, IOP Publishing Ltd, 2017, UNSP 012021  crossref  isi  scopus
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    24. Quapp W., “A Minimal 2D Model of the Free Energy Surface For a Unidirectional Natural Molecular Motor”, J. Math. Chem., 56:4 (2018), 1339–1347  crossref  mathscinet  zmath  isi  scopus
    25. Ustynyuk L.Y., Tikhonov A.N., “The Cytochrome B(6)F Complex: Dft Modeling of the First Step of Plastoquinol Oxidation By the Iron-Sulfur Protein”, J. Organomet. Chem., 867:SI (2018), 290–299  crossref  isi  scopus
    26. Xie D.-F., Yu Ya., Deng Y.-Q., Li J., Liu H.-Y., Zhou S.-D., He X.-J., “Comparative Analysis of the Chloroplast Genomes of the Chinese Endemic Genus Urophysa and Their Contribution to Chloroplast Phylogeny and Adaptive Evolution”, Int. J. Mol. Sci., 19:7 (2018), 1847  crossref  isi  scopus
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