A. V. Grigoryev, A. O. Manturov, “Kinetics of diffusion-limited elongation of DNA fragments”, Izv. Sarat. Univ. Physics, 14:2 (2014), 57

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Izvestiya of Saratov University. Physics, 2014, Volume 14, Issue 2, Pages 57–59
DOI: https://doi.org/10.18500/1817-3020-2014-14-2-57-59 (Mi isuph215)

Physics

Kinetics of diffusion-limited elongation of DNA fragments

A. V. Grigoryev, A. O. Manturov

Saratov State Technical University

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DOI: https://doi.org/10.18500/1817-3020-2014-14-2-57-59

Abstract: The numerical model of the elongation kinetics of the single-stranded DNA has been proposed and studied. The proposed model is based on the principles of the phenomenological modelling and implemented as diffusion cellular automata. The analytical and numerical estimates of the elongation reaction rate for different concentrations of nucleotides has been obtained. The possibility of nucleotide binding delays with reducing the concentration of one of the nucleotides in the solution is shown.

Keywords: deoxyribonucleic acid (DNA), elongation, diffusion, kinetics of the polymerization, nucleotides, DNA polymerase.

Document Type: Article

UDC: 577.213.44; 577.31; 577.212.3

Language: Russian

Citation: A. V. Grigoryev, A. O. Manturov, “Kinetics of diffusion-limited elongation of DNA fragments”, Izv. Sarat. Univ. Physics, 14:2 (2014), 57–59

Citation in format AMSBIB

\Bibitem{GriMan14}

\by A.~V.~Grigoryev, A.~O.~Manturov

\paper Kinetics of diffusion-limited elongation of DNA fragments

\jour Izv. Sarat. Univ. Physics

\yr 2014

\vol 14

\issue 2

\pages 57--59

\mathnet{http://mi.mathnet.ru/isuph215}

\crossref{https://doi.org/10.18500/1817-3020-2014-14-2-57-59}

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