Determining the directionality of coupling between time series extracted from biological data of rats by modeling the phase dynamics of periodic processes

The method of identifying the direction of the coupling between oscillators based on the simulation of phase dynamics of weakly coupled and weakly noisy periodic processes is used to determine the direction of the coupling between time series extracted from biological signals. Neuronal activity, arterial pressure and respiratory rate of anesthetized rats were used as initial data. Various options for the direction of the coupling between the analyzed time series were revealed.