I. A. Doroshenko, K. G. Aminulla, V. N. Azev, T. M. Kulinich, V. A. Vasilichin, A. A. Shtil, T. A. Podrugina, “Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents”, Mendeleev Commun., 31:5 (2021), 615

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Mendeleev Communications, 2021, Volume 31, Issue 5, Pages 615–617
DOI: https://doi.org/10.1016/j.mencom.2021.09.008 (Mi mendc1000)

This article is cited in 11 scientific papers (total in 11 papers)

Communications

Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents

I. A. Doroshenko^a, K. G. Aminulla^a, V. N. Azev^b, T. M. Kulinich^c, V. A. Vasilichin^a, A. A. Shtil^ad, T. A. Podrugina^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Branch of M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
^c Russian Scientific Center of Roentgenoradiology, Moscow, Russian Federation
^d N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation

Full-text PDF (421 kB) Citations (11) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2021.09.008

Graphic abstract: Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents

Abstract: New β-alanine modified tricarbocyanines containing various substituents at quaternized nitrogen atoms were obtained. The peptide synthesis method has been utilized for further conjugation thus giving promising tricarbocyanines containing two sulfonate groups and total negative charge of the fluorophore.

Keywords: fluorophores, conjugates, β-alanine, cell-penetrating peptides, tricarbocyanine dyes, Fluorescent markers.

Bibliographic databases:

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(970.0 Kb)

Citation: I. A. Doroshenko, K. G. Aminulla, V. N. Azev, T. M. Kulinich, V. A. Vasilichin, A. A. Shtil, T. A. Podrugina, “Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents”, Mendeleev Commun., 31:5 (2021), 615–617

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This publication is cited in the following 11 articles:

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