Abstract:
A new synthesis of α-trifluoromethylstyrenes from aromatic ketones and (trifluoromethyl) trimethylsilane is described. The reaction involves nucleophilic trifluoromethylation and elimination of trimethylsilanol, which are performed within one reaction flask.
Citation:
V. V. Levin, A. D. Dilman, “One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent”, Mendeleev Commun., 31:5 (2021), 684–685
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https://www.mathnet.ru/eng/mendc1022
https://www.mathnet.ru/eng/mendc/v31/i5/p684
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