Hayashi ligand-based rhodium complex in carbon monoxide and molecular hydrogen-assisted reductive amination

The CO- and H₂-assisted reductive amination of carbonyl compounds catalyzed by stable chiral Hayashi ligand-based rhodium complex afforded the racemic amines in moderate yields. The racemic outcome of the process results from the elimination of the chiral ligand from the catalyst under the action of hydrogen or carbon monoxide as reductants.