N. S. Kuzmina, V. F. Otvagin, L. V. Krylova, A. V. Nyuchev, Yu. V. Romanenko, O. I. Koifman, I. V. Balalaeva, A. Yu. Fedorov, “Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates”, Mendeleev Commun., 30:2 (2020), 159

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Mendeleev Communications, 2020, Volume 30, Issue 2, Pages 159–161
DOI: https://doi.org/10.1016/j.mencom.2020.03.009 (Mi mendc1133)

This article is cited in 14 scientific papers (total in 14 papers)

Communications

Synthesis and antiproliferative activity of new chlorin e₆ glycoconjugates

N. S. Kuzmina^a, V. F. Otvagin^a, L. V. Krylova^a, A. V. Nyuchev^a, Yu. V. Romanenko^b, O. I. Koifman^b, I. V. Balalaeva^a, A. Yu. Fedorov^a

^a N.I. Lobachevsky State University of Nizhni Novgorod, Nizhni Novgorod, Russian Federation
^b Research Institute of Macroheterocycles, Ivanovo State University of Chemistry and Technology, Ivanovo, Russian Federation

Full-text PDF (3997 kB) Citations (14) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2020.03.009

Graphic abstract: Synthesis and antiproliferative activity of new chlorin <i>e</i><sub>6</sub> glycoconjugates

Abstract: New water soluble conjugates of chlorin e₆ derivative–zinc complex with β-d-galactose or β-d-glucose have been synthesized as potential agents for the photodynamic therapy of cancer. They exhibit photoinduced cytotoxicity at low micromolar concentrations with IC_50(dark)/IC_50(light) ratio of ∼50.

Keywords: chlorin e₆, glycoconjugate, water soluble, A431 cells, photodynamic therapy.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(1.3 Mb)

Citation: N. S. Kuzmina, V. F. Otvagin, L. V. Krylova, A. V. Nyuchev, Yu. V. Romanenko, O. I. Koifman, I. V. Balalaeva, A. Yu. Fedorov, “Synthesis and antiproliferative activity of new chlorin e₆ glycoconjugates”, Mendeleev Commun., 30:2 (2020), 159–161

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https://www.mathnet.ru/eng/mendc1133

https://www.mathnet.ru/eng/mendc/v30/i2/p159

This publication is cited in the following 14 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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