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Mendeleev Communications, 2020, Volume 30, Issue 4, Pages 498–499
DOI: https://doi.org/10.1016/j.mencom.2020.07.031
(Mi mendc1236)
 

This article is cited in 25 scientific papers (total in 25 papers)

Communications

Antibacterial activity of 2-amino-3-cyanopyridine derivatives

I. G. Mamedova, F. N. Naghieva, A. M. Maharramova, O. Uwangueb, A. Farewellb, P. Sunnerhagenb, M. Erdelyic

a Department of Chemistry, Baku State University, Baku, Azerbaijan
b Department of Chemistry and Molecular Biology and the Center for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden
c Department of Chemistry, Uppsala University, Uppsala, Sweden
Abstract: New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the Gram-positive B. subtilis was tested, the only representative showed a substantial antimicrobial effect.
Keywords: 3,5-dicyanopyridines, antimicrobial activity, halogen bonding, bacteria, E. coli, B. subtilis.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (2.8 Mb)


Citation: I. G. Mamedov, F. N. Naghiev, A. M. Maharramov, O. Uwangue, A. Farewell, P. Sunnerhagen, M. Erdelyi, “Antibacterial activity of 2-amino-3-cyanopyridine derivatives”, Mendeleev Commun., 30:4 (2020), 498–499
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  • https://www.mathnet.ru/eng/mendc/v30/i4/p498
  • This publication is cited in the following 25 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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