S. A. Gorbatov, D. Yu. Uvarov, A. M. Scherbakov, I. V. Zavarzin, Yu. A. Volkova, A. Romieu, “A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells”, Mendeleev Commun., 30:6 (2020), 750

Mendeleev Communications

RUS ENG

JOURNALS PEOPLE ORGANISATIONS CONFERENCES SEMINARS VIDEO LIBRARY PACKAGE AMSBIB

JavaScript is disabled in your browser. Please switch it on to enable full functionality of the website

	General information
	Latest issue
	Archive

	Search papers
	Search references

	RSS
	Latest issue
	Current issues
	Archive issues
	What is RSS

Mendeleev Commun.:
Year:
Volume:
Issue:
Page:
	Find

Personal entry:
Login:
Password:
	Save password
	Enter
	Forgotten password?
	Register

Mendeleev Communications, 2020, Volume 30, Issue 6, Pages 750–752
DOI: https://doi.org/10.1016/j.mencom.2020.11.020 (Mi mendc1313)

This article is cited in 5 scientific papers (total in 5 papers)

Communications

A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells

S. A. Gorbatov^ab, D. Yu. Uvarov^a, A. M. Scherbakov^c, I. V. Zavarzin^a, Yu. A. Volkova^a, A. Romieu^b

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR 6302, CNRS, Univ.Bourgogne
^c N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation

Full-text PDF (653 kB) Citations (5) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2020.11.020

Graphic abstract: A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells

Abstract: The development of effective methods for real-time monitoring of nitroreductase (NTR) activity is of great significance for medical diagnosis and cancer research. Here, we present a novel water-soluble BODIPY-based chemodosimeter (NBB) for imaging the hypoxic status of human non-small-cell lung cancer A549 cells. We assume that ‘on–off’ response of NBB is activated by the NTRmediated reductive release of meso-phenol BODIPY dye resulting in unusual fluorescence.

Keywords: BODIPY, fluorescent probe, hypoxia, lung cancer, nitroreductase.

Bibliographic databases:

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(1.1 Mb)

Citation: S. A. Gorbatov, D. Yu. Uvarov, A. M. Scherbakov, I. V. Zavarzin, Yu. A. Volkova, A. Romieu, “A novel water-soluble BODIPY dye as red fluorescent probe for imaging hypoxic status of human cancer cells”, Mendeleev Commun., 30:6 (2020), 750–752

Linking options:

https://www.mathnet.ru/eng/mendc1313

https://www.mathnet.ru/eng/mendc/v30/i6/p750

This publication is cited in the following 5 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

Registration to the website

Logotypes