V. V. Musiyak, D. A. Gruzdev, M. A. Kravchenko, D. V. Vakhrusheva, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Synthesis and antimycobacterial activity of purine conjugates with (S)-lysine and (S)-ornithine”, Mendeleev Commun., 29:1 (2019), 11

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Mendeleev Communications, 2019, Volume 29, Issue 1, Pages 11–13
DOI: https://doi.org/10.1016/j.mencom.2019.01.002 (Mi mendc1404)

This article is cited in 12 scientific papers (total in 12 papers)

Communications

Synthesis and antimycobacterial activity of purine conjugates with (S)-lysine and (S)-ornithine

V. V. Musiyak^a, D. A. Gruzdev^ab, M. A. Kravchenko^c, D. V. Vakhrusheva^c, G. L. Levit^ab, V. P. Krasnov^ab, V. N. Charushin^ab

^a I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
^c Ural Research Institute for Phthisiopulmonology, Ekaterinburg, Russian Federation

Full-text PDF (226 kB) Citations (12) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2019.01.002

Graphic abstract: Synthesis and antimycobacterial activity of purine conjugates with (<i>S</i>)-lysine and (<i>S</i>)-ornithine

Abstract: Novel purin-6-yl, 2-aminopurin-6-yl and N-(purin-6-yl)glycyl derivatives of (S)-lysine and (S)-ornithine with free α-functional groups, as well as compounds containing N⁹-(2-hydroxy-ethoxy)methyl substituent in the purine core have been synthesized and tested for their inhibitory effect against Mycobacterium tuberculosis strains. Among the synthesized conjugates, one compound exhibiting a significant level of antimycobacterial activity has been found.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(447.9 Kb)

Citation: V. V. Musiyak, D. A. Gruzdev, M. A. Kravchenko, D. V. Vakhrusheva, G. L. Levit, V. P. Krasnov, V. N. Charushin, “Synthesis and antimycobacterial activity of purine conjugates with (S)-lysine and (S)-ornithine”, Mendeleev Commun., 29:1 (2019), 11–13

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https://www.mathnet.ru/eng/mendc1404

https://www.mathnet.ru/eng/mendc/v29/i1/p11

This publication is cited in the following 12 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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