Abstract:
Novel N-pyrimidyl amidines of alycyclic acids were obtained in one step from of 4-azidopyrimidines and endocyclic enamines. The reaction mechanism involves [3 + 2]-addition of azide at the double bond followed by cleavage of thus formed 1,2,3-triazoline ring, and a contraction of alicycle.
Citation:
N. A. Beliaev, T. V. Beryozkina, G. Lubec, V. A. Bakulev, “A catalyst-free one-step synthesis of N-pyrimidinyl amidines from endocyclic enamines and 4-azidopyrimidines”, Mendeleev Commun., 29:1 (2019), 50–52
Linking options:
https://www.mathnet.ru/eng/mendc1417
https://www.mathnet.ru/eng/mendc/v29/i1/p50
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