G. V. Pazynina, S. V. Tsygankova, I. M. Ryzhov, N. V. Shilova, S. M. Polyakova, A. S. Paramonov, A. A. Formanovsky, N. V. Bovin, “Synthesis of GalNGcα1-3GalNAcα disaccharide and its interaction with human blood antibodies”, Mendeleev Commun., 29:3 (2019), 254

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Mendeleev Communications, 2019, Volume 29, Issue 3, Pages 254–255
DOI: https://doi.org/10.1016/j.mencom.2019.05.004 (Mi mendc1487)

This article is cited in 1 scientific paper (total in 1 paper)

Communications

Synthesis of GalNGcα1-3GalNAcα disaccharide and its interaction with human blood antibodies

G. V. Pazynina, S. V. Tsygankova, I. M. Ryzhov, N. V. Shilova, S. M. Polyakova, A. S. Paramonov, A. A. Formanovsky, N. V. Bovin

M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Full-text PDF (281 kB) Citations (1) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2019.05.004

Graphic abstract: Synthesis of GalNGcα1-3GalNAcα disaccharide and its interaction with human blood antibodies

Abstract: We have synthesized GalNGcα1-3GalNAcα disaccharide, a glycoloyl analogue of GalNAcα1-3GalNAcα known as the core 5 motif of mucin-type glycoproteins, and investigated how this structural variation affects the interaction with human natural antibodies. In contrast to the case of the Neu5NGc/Neu5NAc pair, the additional glycoloyl OH group in GalNGcα1-3GalNAcα markedly reduced the antigenicity of the GalNGcα moiety.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(348.7 Kb)

Citation: G. V. Pazynina, S. V. Tsygankova, I. M. Ryzhov, N. V. Shilova, S. M. Polyakova, A. S. Paramonov, A. A. Formanovsky, N. V. Bovin, “Synthesis of GalNGcα1-3GalNAcα disaccharide and its interaction with human blood antibodies”, Mendeleev Commun., 29:3 (2019), 254–255

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https://www.mathnet.ru/eng/mendc1487

https://www.mathnet.ru/eng/mendc/v29/i3/p254

This publication is cited in the following 1 articles:

Citing articles in Google Scholar: Russian citations, English citations
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