M. A. Epishina, A. S. Kulikov, L. L. Fershtat, I. V. Ananyev, N. N. Makhova, “Synthesis of new pharmacologically oriented heterocyclic ensembles, [2-(1H-pyrazol-1-yl)thiazol-4-yl]furoxans”, Mendeleev Commun., 29:3 (2019), 288

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Mendeleev Communications, 2019, Volume 29, Issue 3, Pages 288–291
DOI: https://doi.org/10.1016/j.mencom.2019.05.015 (Mi mendc1498)

This article is cited in 8 scientific papers (total in 8 papers)

Communications

Synthesis of new pharmacologically oriented heterocyclic ensembles, [2-(1H-pyrazol-1-yl)thiazol-4-yl]furoxans

M. A. Epishina^a, A. S. Kulikov^a, L. L. Fershtat^a, I. V. Ananyev^bc, N. N. Makhova^a

^a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^c G.V. Plekhanov Russian University of Economics, Moscow, Russian Federation

Full-text PDF (313 kB) Citations (8) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2019.05.015

Graphic abstract: Synthesis of new pharmacologically oriented heterocyclic ensembles, [2-(1<i>H</i>-pyrazol-1-yl)thiazol-4-yl]furoxans

Abstract: The effective synthesis of pharmacologically oriented heterocyclic ensembles, [2-(1H-pyrazol-1-yl)thiazol-4-yl]furoxans, comprising furoxan moiety as NO-donor and pharmacophoric pyrazolylthiazole fragment is based on the condensation of (2-hydrazinylthiazol-4-yl)furoxan hydrobromides with linear 1,3-diketones. The reaction proceeds through hydroxypyrazoline intermediate.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(2.8 Mb)

Citation: M. A. Epishina, A. S. Kulikov, L. L. Fershtat, I. V. Ananyev, N. N. Makhova, “Synthesis of new pharmacologically oriented heterocyclic ensembles, [2-(1H-pyrazol-1-yl)thiazol-4-yl]furoxans”, Mendeleev Commun., 29:3 (2019), 288–291

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https://www.mathnet.ru/eng/mendc1498

https://www.mathnet.ru/eng/mendc/v29/i3/p288

This publication is cited in the following 8 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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