Abstract:
Regiospecific ribosylation of 3-polyfluoroalkyl-5-phenylpyrazoles with 1,2,3,5-tetra-O-acetyl-β-d-ribofuranose in the presence of tin(iv) chloride followed by deacetylation affords 1-(β-d-ribofuranosyl)-3-polyfluoroalkyl-5-phenyl- 1H-pyrazoles. These derivatives as well as starting pyrazoles were tested for anti-influenza activity.
Bibliographic databases:
Document Type:
Article
Language: English
Citation:
A. E. Ivanova, Ya. V. Burgart, V. I. Saloutin, Ya. R. Orshanskaya, V. V. Zarubaev, “β-d-Ribofuranosyl substituted polyfluoroalkylpyrazoles and their activity against the influenza virus”, Mendeleev Commun., 28:1 (2018), 52–54
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https://www.mathnet.ru/eng/mendc1661
https://www.mathnet.ru/eng/mendc/v28/i1/p52
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