Abstract:
Intramolecular cyclization of α-bromoacyl derivatives of α-hydroxy acids affords 1,4-dioxane-2,5-diones. The method is suitable to obtain mono- and disubstituted products, the latter being formed stereoselectively as (S,S)-diastereomers, as confirmed by DFT modeling.
Citation:
B. A. Lozhkin, A. V. Shlyakhtin, V. V. Bagrov, P. V. Ivchenko, I. E. Nifant'ev, “Effective stereoselective approach to substituted 1,4-dioxane-2,5-diones as prospective substrates for ring-opening polymerization”, Mendeleev Commun., 28:1 (2018), 61–63
Linking options:
https://www.mathnet.ru/eng/mendc1664
https://www.mathnet.ru/eng/mendc/v28/i1/p61
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