Abstract:
(2R,3R)-N-(3-Methoxy-2,3-dioxopropyl)-N-(4-methoxy-phenyl)-2,3-epoxybutanamide on treatment with strong bases (LDA, LHMDS) gives 3-[(1R)-1-hydroxyethyl]azetidin-2-one derivative, while the N-(3-methoxy-2-methylidene-3-oxo-propyl) analogue undergoes fragmentation.
Citation:
N. K. Selezneva, Z. R. Valiullina, L. S. Khasanova, F. A. Gimalova, R. Z. Biglova, M. S. Miftakhov, “Novel azetidinones for carbapenems and fragmentation in the allylamine precursor analogue”, Mendeleev Commun., 28:2 (2018), 131–132
Linking options:
https://www.mathnet.ru/eng/mendc1687
https://www.mathnet.ru/eng/mendc/v28/i2/p131
This publication is cited in the following 4 articles: