Abstract:
Multi-liposomal containers were prepared via electrostatic adsorption of 50 nm anionic liposomes on the surface of cationic chitosan nanoparticles (nanogels) 270 nm in diameter. The containers are stable in aqueous-salt solutions but degrade in the presence of proteolytic enzymes down to 10–15 nm particles and release water-soluble substances encapsulated into the adsorbed liposomes. Based on the kinetic data, the mechanism of the release is discussed.
Citation:
A. A. Yaroslavov, A. A. Efimova, F. D. Mulashkin, G. N. Rudenskaya, G. G. Krivtsov, “Biodegradable liposome–chitosan complexes: enzyme-mediated release of encapsulated substances”, Mendeleev Commun., 28:2 (2018), 140–142
Linking options:
https://www.mathnet.ru/eng/mendc1691
https://www.mathnet.ru/eng/mendc/v28/i2/p140
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