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Mendeleev Communications, 2018, Volume 28, Issue 6, Pages 579–581
DOI: https://doi.org/10.1016/j.mencom.2018.11.004
(Mi mendc1841)
 

This article is cited in 5 scientific papers (total in 5 papers)

Communications

A new synthetic route to chiral 3-aryl-5-ethyl-1,4,2-oxazaphosphorines

K. E. Metlushkaa, D. N. Sadkovaa, K. A. Nikitinaa, Z. R. Yamaleevaa, K. A. Ivshinab, O. N. Kataevaa, V. A. Alfonsova

a A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
b A.M. Butlerov Chemistry Institute, Kazan Federal University, Kazan, Russian Federation
Abstract: Diastereoselective synthesis of racemic and enantiopure 3-aryl-5-ethyl-1,4,2-oxazaphosphorines, including those bearing phenolic hydroxyl groups in the exocyclic aromatic fragment, was implemented by the reaction of imines derived from (±)-and (R)-(−)-2-aminobutan-1-ol and (hydroxy)benzaldehydes with triethyl phosphite and trifluoroacetic acid, followed by the one-pot dealkylation of the intermediate esters.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (769.1 Kb)


Citation: K. E. Metlushka, D. N. Sadkova, K. A. Nikitina, Z. R. Yamaleeva, K. A. Ivshin, O. N. Kataeva, V. A. Alfonsov, “A new synthetic route to chiral 3-aryl-5-ethyl-1,4,2-oxazaphosphorines”, Mendeleev Commun., 28:6 (2018), 579–581
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  • https://www.mathnet.ru/eng/mendc/v28/i6/p579
  • This publication is cited in the following 5 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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