V. V. Abzianidze, K. P. Bolshakova, D. S. Prokofieva, A. O. Berestetskiy, V. A. Kuznetsov, Yu. G. Trishin, “Synthesis of 7-(4-methylphenyl)thiomethyl and 7-morpholylmethyl derivatives of natural phaeosphaeride A and their cytotoxic activity”, Mendeleev Commun., 27:1 (2017), 82

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Mendeleev Communications, 2017, Volume 27, Issue 1, Pages 82–84
DOI: https://doi.org/10.1016/j.mencom.2017.01.026 (Mi mendc1903)

This article is cited in 8 scientific papers (total in 8 papers)

Communications

Synthesis of 7-(4-methylphenyl)thiomethyl and 7-morpholylmethyl derivatives of natural phaeosphaeride A and their cytotoxic activity

V. V. Abzianidze^a, K. P. Bolshakova^b, D. S. Prokofieva^a, A. O. Berestetskiy^c, V. A. Kuznetsov^a, Yu. G. Trishin^b

^a Research Institute of Hygiene, Occupational Pathology and Human Ecology, Leningrad region, Russian Federation
^b Saint-Petersburg State University of Industrial Technologies and Design, St. Petersburg, Russian Federation
^c All-Russian Institute of Plant Protection, Federal Agency of Scientific Organizations, Pushkin, St. Petersburg, Russian Federation

Full-text PDF (391 kB) Citations (8) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2017.01.026

Graphic abstract: Synthesis of 7-(4-methylphenyl)thiomethyl and 7-morpholylmethyl derivatives of natural phaeosphaeride A and their cytotoxic activity

Abstract: The herein synthesized 7-(4-methylphenyl)thiomethyl and 7-morpholylmethyl derivatives of natural phaeosphaeride A have lower cytotoxic activity towards the human lung adenocarcinoma A549 cell line compared to phaeosphaeride A. The presence of exocyclic C=C bond and N–OMe group in such compounds is suggested to be a factor in their antitumor activity.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(243.0 Kb)

Citation: V. V. Abzianidze, K. P. Bolshakova, D. S. Prokofieva, A. O. Berestetskiy, V. A. Kuznetsov, Yu. G. Trishin, “Synthesis of 7-(4-methylphenyl)thiomethyl and 7-morpholylmethyl derivatives of natural phaeosphaeride A and their cytotoxic activity”, Mendeleev Commun., 27:1 (2017), 82–84

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https://www.mathnet.ru/eng/mendc1903

https://www.mathnet.ru/eng/mendc/v27/i1/p82

This publication is cited in the following 8 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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