Abstract:
The title compound, a possible precursor of metabolically stable corresponding PGJ2, was obtained from cloprostenol in seven steps. The compound demonstrated cytotoxicity against the HEK 293, Hep G2 and Jurkat cell lines.
Citation:
N. S. Vostrikov, I. F. Lobko, L. V. Spirikhin, Yu. V. Vakhitova, K. K. Pivnitsky, M. S. Miftakhov, “Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity”, Mendeleev Commun., 27:2 (2017), 125–127
Linking options:
https://www.mathnet.ru/eng/mendc1917
https://www.mathnet.ru/eng/mendc/v27/i2/p125
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