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Mendeleev Communications, 2017, Volume 27, Issue 2, Pages 125–127
DOI: https://doi.org/10.1016/j.mencom.2017.03.005
(Mi mendc1917)
 

This article is cited in 9 scientific papers (total in 9 papers)

Communications

Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity

N. S. Vostrikova, I. F. Lobkoa, L. V. Spirikhina, Yu. V. Vakhitovab, K. K. Pivnitskyc, M. S. Miftakhova

a Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
b Institute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, Ufa, Russian Federation
c N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
Abstract: The title compound, a possible precursor of metabolically stable corresponding PGJ2, was obtained from cloprostenol in seven steps. The compound demonstrated cytotoxicity against the HEK 293, Hep G2 and Jurkat cell lines.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.7 Mb)


Citation: N. S. Vostrikov, I. F. Lobko, L. V. Spirikhin, Yu. V. Vakhitova, K. K. Pivnitsky, M. S. Miftakhov, “Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity”, Mendeleev Commun., 27:2 (2017), 125–127
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  • https://www.mathnet.ru/eng/mendc/v27/i2/p125
  • This publication is cited in the following 9 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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