M. G. Khrenova, I. D. Solovyev, G. D. Lapshin, A. P. Savitsky, “Molecular mechanism of interactions between MMP-2 and its oligopeptide-based inhibitors”, Mendeleev Commun., 27:2 (2017), 157

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Mendeleev Communications, 2017, Volume 27, Issue 2, Pages 157–159
DOI: https://doi.org/10.1016/j.mencom.2017.03.017 (Mi mendc1929)

This article is cited in 2 scientific papers (total in 2 papers)

Communications

Molecular mechanism of interactions between MMP-2 and its oligopeptide-based inhibitors

M. G. Khrenova^ab, I. D. Solovyev^ab, G. D. Lapshin^a, A. P. Savitsky^a

^a A.N. Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Full-text PDF (511 kB) Citations (2)

DOI: https://doi.org/10.1016/j.mencom.2017.03.017

Graphic abstract: Molecular mechanism of interactions between MMP-2 and its oligopeptide-based inhibitors

Abstract: Taking matrix metalloproteinase MMP-2 as an example, we demonstrate that the rational design of oligopeptide-based inhibitors by molecular modeling should involve both a study of interactions in the active sites of the target enzyme and the conformational dynamics of the oligopeptide in solution.

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Document Type: Article

Language: English

Citation: M. G. Khrenova, I. D. Solovyev, G. D. Lapshin, A. P. Savitsky, “Molecular mechanism of interactions between MMP-2 and its oligopeptide-based inhibitors”, Mendeleev Commun., 27:2 (2017), 157–159

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https://www.mathnet.ru/eng/mendc1929

https://www.mathnet.ru/eng/mendc/v27/i2/p157

This publication is cited in the following 2 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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