Abstract:
Available β,γ-enones, the products of nucleophilic addition of ketones to phenylacetylene, react with guanidine in the KOH / DMSO system at 70°C to give 2-aminopyrimidines in up to 72% yield.
Citation:
E. Yu. Schmidt, I. V. Tatarinova, E. V. Ivanova, B. A. Trofimov, “2-Aminopyrimidines in just two steps from ketones, acetylenes and guanidine via β,γ enones”, Mendeleev Commun., 27:3 (2017), 283–284
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https://www.mathnet.ru/eng/mendc1969
https://www.mathnet.ru/eng/mendc/v27/i3/p283
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