Abstract:
New well-soluble in 10% DMSO phosphonate derivatives of substituted benzophenone have been synthesized using different methods. Preliminary computer modeling of proposed structures in the reverse transcriptase HIV-1 hydrophobic pocket suggested these molecules as potential non-nucleoside inhibitors of this enzyme.
Citation:
M. S. Gaman, E. S. Matyugina, M. S. Novikov, D. A. Babkov, P. N. Solyev, S. N. Kochetkov, A. L. Khandazhinskaya, “New benzophenone phosphonate derivatives”, Mendeleev Commun., 27:4 (2017), 346–348
Linking options:
https://www.mathnet.ru/eng/mendc1989
https://www.mathnet.ru/eng/mendc/v27/i4/p346
This publication is cited in the following 2 articles: