Synthesis of hybrid compounds composed of daunorubicin covalently linked with Cp2Fe and CpMn(CO)3

Hybrid molecules wherein five-membered rings of ferrocene or cymanthrene are covalently bonded with the amino group of daunorubicin through a methylene linker, have been synthesized by reductive amination of the corresponding aldehydes [M]C₅H₄CHO {[M] = CpFe or (CO)₃Mn} using daunorubicin as an amine component.