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Mendeleev Communications, 2016, Volume 26, Issue 4, Pages 269–275
DOI: https://doi.org/10.1016/j.mencom.2016.07.001
(Mi mendc2183)
 

This article is cited in 30 scientific papers (total in 30 papers)

Focus Article

Amyloid-β containing isoaspartate 7 as potential biomarker and drug target in Alzheimer's disease

S. A. Kozin, V. A. Mitkevich, A. A. Makarov

V.A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russian Federation
Abstract: Recent data about structure, interaction with biometals, aggregation state, proteolysis by angiotensin converting enzyme, neurotoxicity and amyloidogenicity of amyloid-β containing isoaspartate 7 (isoAsp7-Aβ) in comparison with intact amyloid-β are summarized. Possible role of isoAsp7-Aβ as a prospective biomarker for molecular diagnostics and drug target in anti-amyloid therapy of Alzheimer's disease is discussed.
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Document Type: Article
Language: English


Citation: S. A. Kozin, V. A. Mitkevich, A. A. Makarov, “Amyloid-β containing isoaspartate 7 as potential biomarker and drug target in Alzheimer's disease”, Mendeleev Commun., 26:4 (2016), 269–275
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  • https://www.mathnet.ru/eng/mendc2183
  • https://www.mathnet.ru/eng/mendc/v26/i4/p269
  • This publication is cited in the following 30 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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