Abstract:
Thermally induced non-catalytic assembling of salicylaldehydes and dimedone in water or ethanol affords 9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-ones in 85–95% yields as a sequence of Knoevenagel and Michael reactions.
Citation:
M. N. Elinson, O. O. Sokolova, R. F. Nasybullin, T. A. Zaimovskaya, M. P. Egorov, “Efficient non-catalytic synthesis of substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones from salicylaldehydes and dimedone”, Mendeleev Commun., 25:1 (2015), 19–20
Linking options:
https://www.mathnet.ru/eng/mendc2285
https://www.mathnet.ru/eng/mendc/v25/i1/p19
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