Abstract:
(R)- and (S)-binaphthyl-2,2’-diols (BINOLs) smoothly react with pentafluoropyridine without racemization to give (R)- and (S)-2,2’- bis(tetrafluoropyridin-4-yloxy)-1,1’-binaphthyls. The 2(6)-positioned pyridine fluorine atoms can be replaced with amino moieties by reactions with amines.
Bibliographic databases:
Document Type:
Article
Language: English
Citation:
K. Yu. Koltunov, A. N. Chernov, “BINOL Modification via SNAr Reactions with Pentafluoropyridine”, Mendeleev Commun., 25:1 (2015), 39–40
Linking options:
https://www.mathnet.ru/eng/mendc2293
https://www.mathnet.ru/eng/mendc/v25/i1/p39
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