Abstract:
The sequential reaction of ketones with phenylacetylene in the presence of KOH/DMSO system followed by the treatment of the reaction mixture with HCl and monosubstituted hydrazines leads to pyrazolines and pyrazoles in up to 87% total yield.
Citation:
E. Yu. Schmidt, E. V. Ivanova, N. V. Semenova, I. V. Tatarinova, I. A. Ushakov, B. A. Trofimov, “Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles”, Mendeleev Commun., 25:2 (2015), 131–132
Linking options:
https://www.mathnet.ru/eng/mendc2324
https://www.mathnet.ru/eng/mendc/v25/i2/p131
This publication is cited in the following 12 articles: