Abstract:
1,8-Bis(dimethylamino)naphthalenes bearing 2-positioned trifluoroacetyl or ethoxycarbonyl group on treatment with 2-lithio-1,8-bis-dimethylamino)naphthalene undergo base-promoted transformation into benzo[g]indole derivatives in small to moderate yield, representing previously unknown mode of the pyrrole ring closure which proceeds via deprotonation of the NMe group.
Citation:
S. G. Kachalkina, G. S. Borodkin, A. F. Pozharskii, A. S. Antonov, I. G. Borodkina, Yu. F. Maltsev, E. A. Filatova, A. Filarowski, V. A. Ozeryanskii, “Base-promoted transformation of 2-C(O)R-1,8-bis(dimethylamino)naphthalenes into benzo[g]indole derivatives”, Mendeleev Commun., 25:3 (2015), 182–184
Linking options:
https://www.mathnet.ru/eng/mendc2343
https://www.mathnet.ru/eng/mendc/v25/i3/p182
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