Abstract:
Reaction of N2-protected 2-amino-6-chloropurine with tert-butyl (S)-phenylalaninate, (R)- and (S)-valinates followed by deprotection affords 2-aminopurines bearing at 6-position the corresponding amino acid moieties, whose chiral centre is partially racemized.
Citation:
A. Yu. Vigorov, V. P. Krasnov, D. A. Gruzdev, A. A. Men'shikova, A. M. Demin, G. L. Levit, V. N. Charushin, “Novel synthetic routes to N-(2-amino-9H-purin-6-yl)-substituted amino acids”, Mendeleev Commun., 24:1 (2014), 35–36
Linking options:
https://www.mathnet.ru/eng/mendc2464
https://www.mathnet.ru/eng/mendc/v24/i1/p35
This publication is cited in the following 16 articles: