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Mendeleev Communications, 2012, Volume 22, Issue 5, Pages 273–274
DOI: https://doi.org/10.1016/j.mencom.2012.09.016
(Mi mendc2817)
 

This article is cited in 6 scientific papers (total in 6 papers)

Ultrasound-assisted Synthesis of Azlactone and its Reactions with Nucleophiles

B. V. Paponova, S. V. Lvovb, E. V. Ichetovkinaa, I. A. Panasenkoa, S. G. Stepanianc

a Department of Chemistry, V.N. Karazin Khar'kov National University, Khar'kov, Ukraine
b Research Institute of Biology, V.N. Karazin Khar'kov National University, Khar'kov, Ukraine
c B.I. Verkin Physicotechnical Institute for Low Temperatures, National Academy of Sciences of Ukraine, Kharkov, Ukraine
Abstract: 4-(2-Oxoindolin-3-ylidene)-2-phenyl-5(4H)-oxazolone (azlactone) was synthesized as a mixture of E- and Z-isomers by ultrasound-assisted Erlenmeyer–Plöchl reaction between isatin and N-benzoylglycine. Treatment of azlactone with nucleophiles causes opening of its oxazolone moiety.
Keywords: Oxindole, azlactone, Erlenmeyer-Plöchl reaction, ultrasound.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.5 Mb)


Citation: B. V. Paponov, S. V. Lvov, E. V. Ichetovkina, I. A. Panasenko, S. G. Stepanian, “Ultrasound-assisted Synthesis of Azlactone and its Reactions with Nucleophiles”, Mendeleev Commun., 22:5 (2012), 273–274
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  • https://www.mathnet.ru/eng/mendc/v22/i5/p273
  • This publication is cited in the following 6 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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