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This article is cited in 6 scientific papers (total in 6 papers)
Ultrasound-assisted Synthesis of Azlactone and its Reactions with Nucleophiles
B. V. Paponova, S. V. Lvovb, E. V. Ichetovkinaa, I. A. Panasenkoa, S. G. Stepanianc a Department of Chemistry, V.N. Karazin Khar'kov National University, Khar'kov, Ukraine
b Research Institute of Biology, V.N. Karazin Khar'kov National University, Khar'kov, Ukraine
c B.I. Verkin Physicotechnical Institute for Low Temperatures, National Academy of Sciences of Ukraine, Kharkov, Ukraine
Abstract:
4-(2-Oxoindolin-3-ylidene)-2-phenyl-5(4H)-oxazolone (azlactone) was synthesized as a mixture of E- and Z-isomers by ultrasound-assisted Erlenmeyer–Plöchl reaction between isatin and N-benzoylglycine. Treatment of azlactone with nucleophiles causes opening of its oxazolone moiety.
Keywords:
Oxindole, azlactone, Erlenmeyer-Plöchl reaction, ultrasound.
Citation:
B. V. Paponov, S. V. Lvov, E. V. Ichetovkina, I. A. Panasenko, S. G. Stepanian, “Ultrasound-assisted Synthesis of Azlactone and its Reactions with Nucleophiles”, Mendeleev Commun., 22:5 (2012), 273–274
Linking options:
https://www.mathnet.ru/eng/mendc2817 https://www.mathnet.ru/eng/mendc/v22/i5/p273
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