I. V. Vystorop, N. P. Konovalova, T. E. Sashenkova, E. N. Berseneva, A. V. Chernyak, B. S. Fedorov, R. G. Kostyanovsky, “1-Hydroxy-8-methyl-1,4,8-triazaspiro[4.5]decan-2-one and its (±)-3-methyl homologue: regioselective synthesis and in vivo evaluation as adjuvants in leukemia chemotherapy”, Mendeleev Commun., 21:5 (2011), 239

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Mendeleev Communications, 2011, Volume 21, Issue 5, Pages 239–241
DOI: https://doi.org/10.1016/j.mencom.2011.09.002 (Mi mendc2929)

This article is cited in 5 scientific papers (total in 5 papers)

1-Hydroxy-8-methyl-1,4,8-triazaspiro[4.5]decan-2-one and its (±)-3-methyl homologue: regioselective synthesis and in vivo evaluation as adjuvants in leukemia chemotherapy

I. V. Vystorop^a, N. P. Konovalova^a, T. E. Sashenkova^a, E. N. Berseneva^a, A. V. Chernyak^a, B. S. Fedorov^a, R. G. Kostyanovsky^b

^a Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
^b N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russian Federation

Full-text PDF (370 kB) Citations (5) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2011.09.002

Abstract: Condensation of glycine and dl-alanine hydroxamic acids with 1-methyl-4-piperidone regioselectively gave the corresponding titled spiro piperidine hydroxyimidazolidinones capable of enhancing sensitivity of P388 and L1210 leukemias in mice models to the known anticancer drugs cisplatin and cyclophosphamide.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(168.2 Kb)

Citation: I. V. Vystorop, N. P. Konovalova, T. E. Sashenkova, E. N. Berseneva, A. V. Chernyak, B. S. Fedorov, R. G. Kostyanovsky, “1-Hydroxy-8-methyl-1,4,8-triazaspiro[4.5]decan-2-one and its (±)-3-methyl homologue: regioselective synthesis and in vivo evaluation as adjuvants in leukemia chemotherapy”, Mendeleev Commun., 21:5 (2011), 239–241

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https://www.mathnet.ru/eng/mendc/v21/i5/p239

This publication is cited in the following 5 articles:

Citing articles in Google Scholar: Russian citations, English citations
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