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This article is cited in 12 scientific papers (total in 12 papers)
Bromination of indomethacin
A. V. Ivachtchenkoab, P. M. Yamanushkina, O. D. Mitkina, O. I. Kiselevc a Department of Organic Chemistry,
Chemical Diversity Research Institute, Khimki, Moscow Region, Russian Federation
b ChemDiv Inc., San Diego, CA, USA
c A.A. Smorodintsev Research Institute of Influenza, St. Petersburg, Russian Federation
Abstract:
Treatment of indomethacin with N-bromosuccinimide in AcOH results in bromination in aromatic positions 4 and 6, while the use of tetrachloromethane allows ultimate bromination at the C(2) Me group of the indole moiety to proceed.
Citation:
A. V. Ivachtchenko, P. M. Yamanushkin, O. D. Mitkin, O. I. Kiselev, “Bromination of indomethacin”, Mendeleev Commun., 20:2 (2010), 111–112
Linking options:
https://www.mathnet.ru/eng/mendc3007 https://www.mathnet.ru/eng/mendc/v20/i2/p111
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