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Mendeleev Communications, 2010, Volume 20, Issue 6, Pages 323–325
DOI: https://doi.org/10.1016/j.mencom.2010.11.007
(Mi mendc3080)
 

This article is cited in 18 scientific papers (total in 18 papers)

Design, synthesis and biotest of a bicyclo[3.3.1]nonane analogue of 2-amino-5,6-dihydro-4H-1,3-thiazine

O. N. Zefirovaab, E. V. Nurievaa, V. I. Chupakhinb, I. S. Semenovaa, D. I. Peregudc, M. V. Onufrievd, N. V. Gulyaevad

a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
b Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
c National Research Center on Addictions, Ministry of Health and Social Development of the Russian Federation, Moscow, Russian Federation
d Institute for Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russian Federation
Abstract: To enhance the lipophilicity of the NO-synthase inhibitor 2-amino-5,6-dihydro-4H-1,3-thiazine, its bridgehead analogue was suggested on the basis of molecular modeling; the synthetic routes to new 3-thia-1-azabicyclo[3.3.1]nonane derivatives and the results of their biological testing are presented.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (114.9 Kb)


Citation: O. N. Zefirova, E. V. Nurieva, V. I. Chupakhin, I. S. Semenova, D. I. Peregud, M. V. Onufriev, N. V. Gulyaeva, “Design, synthesis and biotest of a bicyclo[3.3.1]nonane analogue of 2-amino-5,6-dihydro-4H-1,3-thiazine”, Mendeleev Commun., 20:6 (2010), 323–325
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  • https://www.mathnet.ru/eng/mendc/v20/i6/p323
  • This publication is cited in the following 18 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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