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Mendeleev Communications, 2024, Volume 34, Issue 1, Pages 18–21
DOI: https://doi.org/10.1016/j.mencom.2024.01.006
(Mi mendc31)
 

This article is cited in 8 scientific papers (total in 8 papers)

Communications

Doxorubicin delivery systems based on polypeptide nanoparticles for subcutaneous administration in cancer therapy

N. N. Sudarevaab, I. I. Tarasenkoa, D. N. Suslovc, O. M. Suvorovaa, K. A. Kolbea, G. Y. Yukinab, M. L. Tyndykc, Yu. G. Zmitrichenkoc, E. G. Korzhikova-Vlakhad

a Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russian Federation
b I.P. Pavlov First St. Petersburg State Medical University, St. Petersburg, Russian Federation
c N.N. Petrov National Medical Research Center of Oncology, St. Petersburg, Russian Federation
d Institute of Chemistry, St. Petersburg State University, St. Petersburg, Russian Federation
Abstract: Polypeptide-based doxorubicin delivery systems were prepared and their physicochemical and functional properties, such as size, encapsulation efficiency, stability, release of doxorubicin in various media and cytotoxicity, were characterized. An in vivo study revealed an effective reduction of tumor growth when these systems were administered subcutaneously.
Keywords: doxorubicin, synthetic polypeptides, nanoparticles, delivery systems, cancer treatment, subcutaneous administration.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (835.7 Kb)


Citation: N. N. Sudareva, I. I. Tarasenko, D. N. Suslov, O. M. Suvorova, K. A. Kolbe, G. Y. Yukina, M. L. Tyndyk, Yu. G. Zmitrichenko, E. G. Korzhikova-Vlakh, “Doxorubicin delivery systems based on polypeptide nanoparticles for subcutaneous administration in cancer therapy”, Mendeleev Commun., 34:1 (2024), 18–21
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  • This publication is cited in the following 8 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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