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This article is cited in 22 scientific papers (total in 22 papers)
Design, synthesis and bioactivity of simplified taxol analogues on the basis of bicyclo[3.3.1]nonane derivatives
O. N. Zefirovaa, E. V. Nurievaa, H. Lemckeb, A. A. Ivanovc, N. V. Zyka, D. G. Weissb, S. A. Kuznetsovb, N. S. Zefirova a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
b Institute of Biological Sciences, Cell Biology and Biosystems Technology, University of Rostock, Rostock, Germany
c Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
Abstract:
Four specially designed bicyclo[3.3.1]nonane-based structures were synthesised and found to be cytotoxic at micromolar concentrations and to cause slight non-specific tubulin aggregation.
Citation:
O. N. Zefirova, E. V. Nurieva, H. Lemcke, A. A. Ivanov, N. V. Zyk, D. G. Weiss, S. A. Kuznetsov, N. S. Zefirov, “Design, synthesis and bioactivity of simplified taxol analogues on the basis of bicyclo[3.3.1]nonane derivatives”, Mendeleev Commun., 18:4 (2008), 183–185
Linking options:
https://www.mathnet.ru/eng/mendc3289 https://www.mathnet.ru/eng/mendc/v18/i4/p183
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