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Mendeleev Communications, 2023, Volume 33, Issue 2, Pages 231–233
DOI: https://doi.org/10.1016/j.mencom.2023.02.026
(Mi mendc359)
 

This article is cited in 1 scientific paper (total in 1 paper)

Communications

A simple synthesis of natural spinazarins and their analogues

D. N. Pelageevab, K. L. Borisovaa, S. M. Kovachb, V. V. Makhankova, V. Ph. Anufrieva

a G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russian Federation
b Institute of High Technologies and Advanced Materials, Far Eastern Federal University, Vladivostok, Russian Federation
Abstract: A short simple synthesis of spinazarins (2,3-dihydroxy-naphthazarins or 2,3,5,8-tetrahydroxy-1,4-naphtho-quinones) from available 2,3-dichloronaphthazarin derivatives involves replacement of chlorine atoms with azido groups followed by their acidic hydrolysis. The procedure can be used for the preparative synthesis of natural biologically active spinazarins and their analogues.
Keywords: 5, 8-dihydroxy-1,4-naphthoquinone, naphthazarin, 2,3-dihydroxynaphthazarin, spinazarin, organic azides, hydrolysis, sea urchin pigments.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.8 Mb)


Citation: D. N. Pelageev, K. L. Borisova, S. M. Kovach, V. V. Makhankov, V. Ph. Anufriev, “A simple synthesis of natural spinazarins and their analogues”, Mendeleev Commun., 33:2 (2023), 231–233
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  • This publication is cited in the following 1 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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