|
This article is cited in 6 scientific papers (total in 6 papers)
Solid-state properties of 1,2-epoxy-3-(2-cyanophenoxy)propane, a conglomerate-forming chiral drug precursor
A. A. Bredikhin, Z. A. Bredikhina, D. V. Zakharychev, F. S. Akhatova, D. B. Krivolapov, I. A. Litvinov
A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
Abstract:
Both enantiomers of 1,2-epoxy-3-(2-cyanophenoxy)propane 1a were obtained and converted into enantiomeric bunitrolol hydrochlorides 3 to confirm the configuration of the formers; racemic 1a undergoes spontaneous resolution upon crystallization and could be resolved into individual enantiomers by a preferential crystallization with low efficiency.
Citation:
A. A. Bredikhin, Z. A. Bredikhina, D. V. Zakharychev, F. S. Akhatova, D. B. Krivolapov, I. A. Litvinov, “Solid-state properties of 1,2-epoxy-3-(2-cyanophenoxy)propane, a conglomerate-forming chiral drug precursor”, Mendeleev Commun., 16:5 (2006), 245–247
Linking options:
https://www.mathnet.ru/eng/mendc3607 https://www.mathnet.ru/eng/mendc/v16/i5/p245
|
|
Contact us: