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This article is cited in 10 scientific papers (total in 10 papers)
Transformation of isosteviol oxime to a lactone under Beckmann reaction conditions
O. I. Militsina, G. I. Kovyljaeva, G. A. Bakaleynik, I. Yu. Strobykina, V. E. Kataev, V. A. Alfonsov, R. Z. Musin, D. V. Beskrovny, I. A. Litvinov
A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation
Abstract:
Heating the 16-E-oxime of isosteviol (ent-16-E-hydroxyiminobeyeran-19-oic acid) with concentrated hydrochloric acid (or 25% H2SO4) at 110 °C leads to the formation of lactone of 4α-carboxy-13α-hydroxy-13,16-seco-ent-19-norbeyeran-16-oic acid as the main product, whereas approximately equal quantities of this lactone and lactam of 4α-carboxy-13α-amino-13,16-seco-ent-19-norbeyeran-16-oic acid are formed by heating the 16-E-oxime of isosteviol with concentrated hydrochloric acid in an ampoule at 180 °C.
Citation:
O. I. Militsina, G. I. Kovyljaeva, G. A. Bakaleynik, I. Yu. Strobykina, V. E. Kataev, V. A. Alfonsov, R. Z. Musin, D. V. Beskrovny, I. A. Litvinov, “Transformation of isosteviol oxime to a lactone under Beckmann reaction conditions”, Mendeleev Commun., 15:1 (2005), 27–29
Linking options:
https://www.mathnet.ru/eng/mendc3661 https://www.mathnet.ru/eng/mendc/v15/i1/p27
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