V. V. Spiridonov, A. R. Lukmanova, D. V. Pozdyshev, A. A. Markova, Yu. L. Volodina, G. V. Golovina, V. V. Shakhmatov, V. A. Kuzmin, V. I. Muronetz, A. A. Yaroslavov, “Ionically cross-linked micro-sized hydrogels with encapsulated drug: Structure, cell uptake kinetics and cytotoxicity”, Mendeleev Commun., 33:4 (2023), 553

Mendeleev Communications

RUS ENG

JOURNALS PEOPLE ORGANISATIONS CONFERENCES SEMINARS VIDEO LIBRARY PACKAGE AMSBIB

JavaScript is disabled in your browser. Please switch it on to enable full functionality of the website

	General information
	Latest issue
	Archive

	Search papers
	Search references

	RSS
	Latest issue
	Current issues
	Archive issues
	What is RSS

Mendeleev Commun.:
Year:
Volume:
Issue:
Page:
	Find

Personal entry:
Login:
Password:
	Save password
	Enter
	Forgotten password?
	Register

Mendeleev Communications, 2023, Volume 33, Issue 4, Pages 553–555
DOI: https://doi.org/10.1016/j.mencom.2023.06.036 (Mi mendc457)

This article is cited in 6 scientific papers (total in 6 papers)

Communications

Ionically cross-linked micro-sized hydrogels with encapsulated drug: Structure, cell uptake kinetics and cytotoxicity

V. V. Spiridonov^a, A. R. Lukmanova^b, D. V. Pozdyshev^c, A. A. Markova^d, Yu. L. Volodina^e, G. V. Golovina^d, V. V. Shakhmatov^d, V. A. Kuzmin^d, V. I. Muronetz^c, A. A. Yaroslavov^a

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Department of Materials Science, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^c A.N. Belozersky Research Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^d N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russian Federation
^e N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation

Full-text PDF (854 kB) Citations (6)

DOI: https://doi.org/10.1016/j.mencom.2023.06.036

Graphic abstract: Ionically cross-linked micro-sized hydrogels with encapsulated drug: Structure, cell uptake kinetics and cytotoxicity

Abstract: Micro-sized hydrogels synthesized by electrostatic cross-linking of anionic alginate with Ca²⁺ cations were additionally loaded with cationic fluorescent dye Rhodamine 6B or cationic antitumor antibiotic doxorubicin. Forming complexes with Ca²⁺ alginate hydrogels, doxorubicin retained or even reduced its toxicity to tumor and normal cells. The results can be used to design containers for the encapsulation and delivery of drugs and control their interaction with cells.

Keywords: sodium alginate, cross-linked hydrogels, rhodamine, doxorubicin, intracell migration, cytotoxicity.

Bibliographic databases:

Document Type: Article

Language: English

Citation: V. V. Spiridonov, A. R. Lukmanova, D. V. Pozdyshev, A. A. Markova, Yu. L. Volodina, G. V. Golovina, V. V. Shakhmatov, V. A. Kuzmin, V. I. Muronetz, A. A. Yaroslavov, “Ionically cross-linked micro-sized hydrogels with encapsulated drug: Structure, cell uptake kinetics and cytotoxicity”, Mendeleev Commun., 33:4 (2023), 553–555

Linking options:

https://www.mathnet.ru/eng/mendc457

https://www.mathnet.ru/eng/mendc/v33/i4/p553

This publication is cited in the following 6 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

Registration to the website

Logotypes